I’ve started playing with Pylons and like it so far. It has the rails-ish routing system, but doesn’t have some of the nonsense. Additionally, it’s designed to be open and adaptable, letting you plug in your own ORM or eschew using one entirely (unlike Django which seems to really want you to use their badly crippled ORM).
To make things easier for people running Fedora 8 or other RPM-based Linux distros, I’ve created some spec files and F8 RPMs to let you install Pylons in an RPM-friendly way. The other dependencies (like python-simplejson) can be found already via
yum. Try them, and let me know what you think; I may submit these for F9.
Update: These have been submitted for review.